An interim look at an Alzheimer’s disease clinical trial evaluating an amyloid-targeting treatment from ProMIS Neurosciences showed low rates of brain bleeding and no incidences of brain swelling — results reported Tuesday that suggest the drug could be safer than approved treatments. In a blinded analysis that pooled safety data from patients receiving the ProMIS drug and a placebo, the total rate of ARIA was 4.4%, with all cases mild and asymptomatic, the company said. None of the patients experienced ARIA-E, which is the more severe side effect that causes brain swelling.
All the cases were characterized as ARIA-H, which involves tiny bleeds in the brain. Continue to STAT+ to read the full story…
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